Armando on Twitter: "Gout #rheumatology - gout is a metabolic disorder of purine synthesis - hyperuricaemia (high urate) -> monosodium urate crystals trigger inflammatory response in joints - mechanism of hyperuricaemia is
The Mechanism for How the Thiazide Diuretic, Hydrochlorothiazide (HCTZ), Increases in Uric Acid Levels and Risk for Gout
![Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0009898105000732-gr2.jpg)
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect
![Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0009898105000732-gr1.jpg)
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect
![Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice - Journal of Hepatology Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice - Journal of Hepatology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/e311ade1-5d96-40b8-bbd2-deb8013962fa/fx1_lrg.jpg)
Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice - Journal of Hepatology
![The oxidant-antioxidant paradox mechanisms of uric acid. Circulating... | Download Scientific Diagram The oxidant-antioxidant paradox mechanisms of uric acid. Circulating... | Download Scientific Diagram](https://www.researchgate.net/publication/305392784/figure/fig7/AS:668587916292102@1536415189364/The-oxidant-antioxidant-paradox-mechanisms-of-uric-acid-Circulating-uric-acid-is-a-major.png)
The oxidant-antioxidant paradox mechanisms of uric acid. Circulating... | Download Scientific Diagram
![Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0009898105000732-gr3.jpg)