Home

rüberkommen Beweisen Zivilisation abt 737 mechanism of action TU dich zusammen mit Konzept Teilweise

The regulation of MCL-1 by Noxa expression and the mechanisms of... |  Download Scientific Diagram
The regulation of MCL-1 by Noxa expression and the mechanisms of... | Download Scientific Diagram

Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions  with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2,  Bcl-xL, and Mcl-1 | Molecular and Cellular Biology
Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1 | Molecular and Cellular Biology

Inner Mitochondrial Membrane Disruption Links Apoptotic and  Agonist-Initiated Phosphatidylserine Externalization in Platelets |  Arteriosclerosis, Thrombosis, and Vascular Biology
Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets | Arteriosclerosis, Thrombosis, and Vascular Biology

Targeting BCL-2 in B-cell malignancies and overcoming therapeutic  resistance | Cell Death & Disease
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance | Cell Death & Disease

Genetics and biomarkers in personalisation of lung cancer treatment - The  Lancet
Genetics and biomarkers in personalisation of lung cancer treatment - The Lancet

ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases  antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]
ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist  that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for  Proteasomal Degradation* - Journal of Biological Chemistry
Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation* - Journal of Biological Chemistry

PROTACs are effective in addressing the platelet toxicity associated with  BCL-XL inhibitors
PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts -  ScienceDirect
ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts - ScienceDirect

Proposed model for the synergistic mechanism of ABT-737 and MG-132... |  Download Scientific Diagram
Proposed model for the synergistic mechanism of ABT-737 and MG-132... | Download Scientific Diagram

Mechanisms of potentiation of ABT-737 lethality by strategies targeting...  | Download Scientific Diagram
Mechanisms of potentiation of ABT-737 lethality by strategies targeting... | Download Scientific Diagram

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive  Myc-driven lymphomas | PNAS
In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas | PNAS

Targeting cell death signaling in colorectal cancer: Current strategies and  future perspectives
Targeting cell death signaling in colorectal cancer: Current strategies and future perspectives

Why do BCL-2 inhibitors work and where should we use them in the clinic? |  Cell Death & Differentiation
Why do BCL-2 inhibitors work and where should we use them in the clinic? | Cell Death & Differentiation

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect

ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis  by inducing urothelial carcinoma cell necroptosis
ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis

Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in  Melanoma
Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in Melanoma

Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer  Research
Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer Research

The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of  Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological  Chemistry
The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological Chemistry

Schematic summary of the effects of ABT-737 on human oral cancer cells....  | Download Scientific Diagram
Schematic summary of the effects of ABT-737 on human oral cancer cells.... | Download Scientific Diagram